he kills orochimaru when orochi tries to take sasukes body. then sasuke takes 2 of orochimarus pupils then they go running around till the find the akatsuki and Madara uchiha (first uchiha... he is tobi) then he just drops off then its just about naruto and akatsuki for a while hten at the end of 449 sasuke redies to attack konoha (unknowing that pain ahd allready destroyed it then revived all the dead cause of a change of heart. here is my magna source link
Online Naruto Magna