In Mid-World
When Roland Deschain enters the door to 1964 and drags her into Mid-World, Detta Walker is in control and responds in a hostile manner, calling him a "honky mahfah". Eventually, Odetta Holmes's personality wakes up and tries to dismiss the whole incident as a dream, but eventually realizes the reality of the situation and becomes depressed and hysterical. She eventually finds friendship and love in Eddie Dean, another person drawn from her world; however, the relationship is restricted by Detta's personality.
Detta takes over and escapes when Roland travels through the third door into the mind of Jack Mort. Eddie is left alone in the darkness and paranoid of Detta, who intends to murder him and Roland. She eventually holds Eddie up with Roland's gun and ties him up in ropes before leaving him on the beach to get eaten by lobstrosities.
Roland (in Mort's body in Detta's world) realizes a way to save Odetta's life, and brings Mort down to a subway station. He then calls for both Odetta and Detta to look into the doorway out of Mort's eyes. When Detta and Odetta both look out the doorway, they see each other for the first time and both have combined memories of Mort dropping the brick on their head and then being pushed in front of the train. This has the effect of blending the personalities together, creating Susannah Dean (Susannah because it was the middle name of both Detta and Odetta, and Dean because she is married to Eddie by ka).
Throughout the rest of the series, Susannah remains Eddie's lifelong love and one of Roland's faithful companions. Being a merging of the "good" Odetta and the "bad" Detta, Susannah seems closer to Odetta, and this "part" of her former personnalities never reappears in the novel; on the other hand, the "bad" Detta is often called to the rescue when Susannah's needs to be a little tougher to deal with evil powers such as the demon of the speaking ring, in The Waste Lands or Mia in Song of Susannah.