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After the brutal murder of Eseme Atler's sister, Maybelle, she is taken into custody by Police Chief Gordy McGovern. From the shock of the murder, and her mother's death after their father left, Eseme went mute. At 15 she doesn't fit in at school at all. One day on her way to school she runs into Seth Pasternak; an elleged black market dealer, only 16 years old. Eseme runs and hides, not wanting to know him, afraid she would reveal too much of herself to him. Seth ofcourse, being who he is, shrugged it off. As the day went on Eseme noticed a guy following her, Jake Teran. Jake was asked to watch Eseme and get information out of her for the police.
Eseme and Jake become friends, though she is still afraid of talking. Seth also becomes a friend as Eseme begins to open up. The day seemed plesent, then lunch came. Here is where the troubles began.Vince and Victor (the demon inside Vince) are prevoked by screams. One girl screamed in lunch and Vince went beserk, kidnapping Eseme for some unknown reason.
Eseme is eventually saved.
Some time passes and Eseme and Jake are now a couple and Seth has some run ins with the black market. Eseme seems to be getting attacked by all these beasts left and right. Later Seth's friend Cat Dupree reveals Eseme Atler is the source. A becon of power for demons and especially the Donovan family in which Vince is decended from. Vince and Eseme are 'conected.' After this, Vince merges into a nicer state and ridding himself of Victor, but a new evil comes onto the screen. Damion, who plans on taking over Heven and Earth with Eseme's power.
Eseme is lost on how to control this power, she's never noticed it before. It turns out Damion killed her sister, and his father killed her mother. Everyone is destrought and finds out of Damion's plans.
In the mix of this, Seth and Cat are a couple as well now. Time passes and Eseme's true power becomes more apparent, but it's now time for Damion to make a move. Eseme is kidnapped by him but saved, but not without a little parting present. Damion set out demons, one killing Cat Dupree on Eseme's birthday. Seth is hart broken and goes on a rampage, killing everyone in the hospital. This is even more disturbing knowing that Cat was in fact pregnate at the time with Seth's child.
Eseme soon finds a girl, Jillian, who apperently works secretly as a slave for Damion. Jillian appearently holds Cat's soul along with her own. Seth and Jillian are a couple immediatly. Jillian soon reveals that she works for Damion and helps in the rescue of Eseme when she is captured yet again. The group goes to hell and Eseme is kept locked away while Jillian is caught as well and punished by Damion.
That was the final straw for Jake, Seth and Vince. Seth casted Damion into a sea of soul snachers where Damion was presumed dead. Jillian and Eseme were saved, and Jake blew up Damion's castle. Vince on the otherhand swore revenge on Eseme for betraying him (they had a bond put on them and Eseme left jake for a while for Vince.) and dissapeared.
The blood Murders ended with a funeral for Cat and Kevin, the unborn child, and Eseme being grounded permenetly by Police chief Gordy.

((I may have skipped over some stuff :/ but this is the gist.))